Neuronal Cell Death

Neuronal Cell Death

penheim, 1991; Burek and Oppenheim, 1998). Although Neurons may die at many different developmental stages some of these hypotheses have received experimental and for many different reasons. As in other tissues, difsupport in individual systems, none seems to be generferent stimuli produce quite different morphological ally applicable. Indeed, it remains to be demonstrated that manifestations o...

Effects of Coriandrum sativum extracts on glucose/serum deprivation-induced neuronal cell death

Objective: This study was planned to investigate whetherCoriandrum sativum (C. sativum) is capable of protecting neurons against glucose/serum deprivation (GSD)-induced cytotoxicity. Material and Methods: The PC12 cells were cultivated for 24 h in standard media (high-glucose DMEM containing Fetal Bovine Serum) or for 6 h in GSD condition (glucose-free DMEM, without serum) in the absence or pr...

[Interleukin-1ß, seizures and neuronal cell death].

Epilepsy is a neurological disorder affecting almost 1% of the world population. Experimental human and animal studies suggest that inflammation mediators, like cytokines, participate in the physiopathology of epilepsy. Interleukin-1beta (IL-1ß) could influence susceptibility for seizures, as well as neuronal death caused by seizures, although some findings are contradictory. This document revi...

Neuronal death and survival - targeting glutamate-induced cell death mechanisms

Neuronal cell death: when, why and how.

Apoptosis is recognised increasingly as a prominent event in nervous system development and disease. This form of death appears to obey the same rules in neurones as in other cells, in that it is initiated by similar extracellular perturbations and distinguished by similar morphological and biochemical changes. When neurones die after survival factor withdrawal, gene transcription is important,...